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Tuesday 13 October 2015

International Conference on Sustainable Chemistry &Engineering October 8 - 9, 2015 , Hotel Lalit, Mumbai, India_ SusChemE 2015

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International Conference on Sustainable Chemistry &Engineering
October 8 - 9, 2015 Hotel Lalit, Mumbai, India


Theme :

CATALYZING RESEARCH AND TECHNOLOGY INNOVATION FOR A SUSTAINABLE FUTURE

International Conference

SusChemE aims to provide a high-profile and internationally renowned forum for researches in catalysis science and technology. The conference will cover major themes relevant to the Sustainable Chemistry & Engineering through plenary and keynote lectures and invited talks. Besides oral and poster presentations along with competition for young students will be organized.

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 SOME PICS



With Prerana Tomke, Anilkumar Gupta, Sagar Gadalkar and Govind Waghmare at The Lalit Mumbai.










 

With Anilkumar Gupta and Govind Waghmare at The Lalit Mumbai.




 

 With Sarita Jamdar Gawas, Prerana Tomke and Sonali Sharad Niphadkar at The Lalit Mumbai.

 
 With Wadilal Rathod, Sagar Gadalkar, Sonali Sharad Niphadkar, Anilkumar Gupta, Prerana Tomke and Priyanka Rao at The Lalit Mumbai.



 

WithShweta Pawar  Priyanka Rao, Sarita Jamdar Gawas, Suraj Yadav, Anilkumar Gupta, Sagar Gadalkar, Girish Nhivekar, Sonali Sharad Niphadkar, Neha Gharat, Wadilal Rathod, Prerana Tomke and Chandrakanth Gadipelly.



 



















P046(SusChemE_220) 
Biocatalysis in Synergism with Acoustic Cavitation as a Green Approach to Synthesis Citronellyl Acetate: Optimization and Kinetic Study. Prerana D. Tomke1,, Virendra K. Rathod1*........WILL BE UPDATED 


Prerana Tomke




Hotel Lalit, Mumbai located close to the city's airports and minutes away from business and financial districts, The Lalit Mumbai offers a calm and peaceful oasis for business and leisure travellers. With a soaring seven-storey atrium lobby, one of the largest in Asia and priceless murals, it exudes sheer luxury and opulence. It hosts many national & international Events in Mumbai as well as Conferences in Mumbai.

368 exquisite rooms and suites providing panoramic skyline views, six resplendent dining and nightlife destinations, the award-winning Rejuve – The Spa, and sophisticated event venues ensure that your every expectation is met and exceeded.

One may also choose to stay at The Residency, with 21 fully furnished serviced apartments designed to evoke the urban style and energy of today's Mumbai. These avant-garde one-bedroom, two-bedroom and three-bedroom residences are amongst the most desired serviced apartments in Mumbai.
The Lalit Mumbai is the perfect reflection of this alluring city - dynamic, inspiring and ultra-modern.
Key distances to Hotel Lalit, Mumbai
International Airport-Approx. 950 meters
Lokmanya Tilak Terminus- Approx. 7kms
Bandra Terminus- Approx. 11kms
Dadar Terminus- Approx. 16kms


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Ingrid Mergelsberg. Director Merck & Co., Inc., USA


OCM Member

Ingrid Mergelsberg

Director, Process Chemistry
Merck & Co., Inc.,
USA
Rahway , New Jersey , United States
Merck & Co. , Inc.
2000 Galloping Hill Road
Kenilworth , New Jersey 07033
United States
Ingrid Mergelsberg has completed her PhD in Organic Chemistry from the Albert Ludwig University in Freiburg, Germany and her postdoctoral studies from the Rochester University, NY and Hoffmann LaRoche in Basel, Switzerland.
She has published more than 30 papers and patents and has 27 years of experience in Chemical Development within the Pharmaceutical Industry always looking for opportunities to integrate the principles of green chemistry and engineering into the business of drug discovery and productions.
She currently is a Director of Process Chemistry at Merck.
She has served as a co-chair of the ACS Green Chemistry Institute Pharmaceutical Roundtable for two years and is currently leading the Green Chemistry working group and co-chairing the API (Active Pharmaceutical Ingredient) leadership group at the International Consortium for Innovation and Quality in the Pharmaceutical Industry (IQ Consortium).
LINKS
https://www.linkedin.com/pub/ingrid-mergelsberg/23/217/bb




Rochester University




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SHARMISTHA SINHA, Ph.D. Recipient of the INSA Medal for Young Scientist 2008, Indian National Science Academy, Government of India

SHARMISTHA SINHA
SHARMISTHA SINHA, Ph.D.
Assistant Professor, Institute of Nanoscience and Technology, Mohali, Punjab, India 
Institute of Nano Science and Technology
Habitat Centre, Phase- 10, Sector- 64
Mohali, Punjab - 160062
Phone Numbers : +91-172-2210073/75
Fax Number: +91-172-2211074
E-mail ID: sinhas [at] inst.ac. in
Website: Sinha Lab
Tel: 0172 - 2210075


LINKS
Email Id : sinhas@inst.ac.in

 

Summary

1. Bacterial Microcompartments as Nanoreactors.
2. Protein nanostructures from bacterial microcompartments
3.Functional amyloid as model for studying amyloid aggregation and disaggregation.
Specialties: Protein Chemistry; Protein nanostructures; Amyloidogenic Proteins; Bacterial Genetics; Imaging techniques such as AFM,TEM;Cell Biology and Tissue culture techniques
Sharmistha Sinha

Awards and Distinction:

♦ Recipient of the INSA Medal for Young Scientist 2008, Indian National Science Academy, Government of India.
  •  
    Degrees:
  • Ph.D., Biophysics, Indian Institute of Science (Bangalore, India)
  • 2002 M.Sc. Physical Chemistry; Grade: First Class, Institution: Department of Chemistry, Burdwan University, Burdwan, INDIA 2000
  • B.Sc. Chemistry, Physics, Mathematics. Grade: First Class, Institution: SikshaBhavan, VisvaBharati University, Santiniketan, INDIA

Experience





Postdoc

Iowa State University
February 2010 – October 2013 (3 years 9 months)
Postdoctoral Scientist, Mentoring Graduate and Undergradutae Student




Postdoctoral Researcher

UCLA
April 2008 – February 2010 (1 year 11 months)




PhD Student

Indian Institute of Science
2002 – 2007 (5 years)

  • Past Advisors:
    Thomas A Bobik (as Post Doctoral Fellow)
    Gal Bitan (as Post Doctoral Fellow)
    Avadhesha Surolia (as Post Doctoral Fellow)
    Avadhesha Surolia (as Graduate Student - Ph.D.)
  • Research:
    Engineering Protein Nanostructures from Bacterial Microcompartments
    Bioremediation and waste water management
    Targeting and delivery of biomolecules
  • Other Experience:2006-2013Post doctoral Fellow
  • Honors:2008INSA, Young Scientist Medal
  • Awards and Distinctions
  • a) Recipient of the 2012 Committee for Professional Opportunities for Women Travel Award to attend Biophysical Society 56th Annual Meeting.
  • b) Recipient of the INSA Medal for Young Scientist 2008, Indian National Science Academy, Government of India.
  • c) Recipient of Junior Research Fellowship, Council of Scientific and Industrial Research (CSIR), Government of India, 2002-2004 and its Senior Research Fellowship from Aug 2004.
  • d) Recipient of Merit Scholarship of VisvaBharati University 1997-1999.
  • CV:CV-Sinha-2014.pdf
  • file:///C:/Users/anthonyc/Downloads/CV-Sinha-2014.pdf
  • sharmisthas@gmail.com
Areas of Research Interest
1. Biomaterials based on Prokaryotic Protein Assemblies
2. Biosensors and Bio-targeting
3. Drug design for Protein misfolding diseases 4. Ligand-Protein interactions
5. Protein Structure-Function relationship
6. Genetic engineering of prokaryotic macromolecular assemblies
Research Achievements
1. Microcompartments and Ordered Protein Sheets in Bacteria: Biomedical and Biotechnological Implications (Feb 2010-Present): Bacterial microcompartments (BMC) are 50-100 nm sized all protein organelles that optimize several conditional metabolic reactions in bacteria. Using genetic engineering, electron microscopy, fluorescence spectroscopy and crystallographic structure determination I explored the crucial factors for stability and integrity of such an architecture. These studies have far reaching implications in the field of drug targeting, delivery, bio nano-reactors and bio-fuel production.
2. Drug Design (May 2008-Jan 2010): This project involved understanding the nano structures involved in nucleation of protein aggregation followed by targeting such structures for development of process specific drug for protein aggregation. I used spectroscopic, physiological, structural biological (NMR and MS), and animal model for development of such a drug. This work received a lot of media attention.
3. Molecular Basis of Cataract in Danish Dementia (Nov 2006-Apr 2008): Danish dementia is associated with an early age cataract. I explored the interactions of Danish dementia peptides with the eye lens crystalins and demonstrated using biophysical, cell biological and animal models that crystallins loose their chaperone properties upon interacting with these peptides. I was awarded the INSA Medal for Young Scientist 2008 for this work.
4. Glycosylation in Legume Lectins (Aug 2002-Nov 2006): Using legume lectins as paradigm and with the help of biophysical, biochemical and bioinformatics tools I was able to show the importance of glycosylation in the stability and unfolding pathway of oligomeric proteins.
Patents
37. Sinha,S., P. Talbiersky, A. Lomakin, F.-G. Klärner, T. Schrader, S. Frautschy, and G. Bitan. International Patent Application No. PCT/US2010/026419, titled "Molecular Tweezers for the Treatment of AmyloidRelated Diseases". (Pending)
38. T Schrader, K Hochdorffer, J Marz-Berberich, L Nagel-Steger, G Bitan, S Sinha. International Patent Application No. PCT
Recent Publications
1.  S Sinha, S Cheng, YW Sung, DE McNamara, MR Sawaya, TO Yeates, TA Bobik. Alanine scanning mutagenesis identifies an asparagine-arginine-lysine triad essential to assembly of the shell of the pdu microcompartment. J Mol Biol. 2014;426(12):2328-45.
2. S. Cheng, Fan, C.,S Sinha, T A Bobik The PduQ enzyme is an alcohol dehydrogenase used to recycle NAD+ internally within the Pdumicrocompartment of Salmonella enterica. PlosOne20127(10):e47144.
3. Fan, C.,S. Cheng, S Sinha, T A Bobik.  Interactions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartments.Proc. Natl. Acad. Sc. USA2012109(37):14995-5000.
4. Sinha, S., Lopes, DHJ. And Bitan G, A key role for lysine residues in amyloid beta-protein folding, assembly, and toxicity. ACS Chemical Neuroscience.2012.3 (6): 473–481.
5. S. Sinha, Z. Du, P. Maiti, F.-G. Klärner, T. Schrader, C. Wang, and G. Bitan, Comparison of three amyloid assembly inhibitors – the sugar scyllo-inositol, the polyphenol epigallocatechingallate, and the molecular tweezers CLR01. ACS Chemical Neuroscience.2012 3 (6):451–458.
6. S. Prabhudesai,* S. Sinha*, A. Attar, A. Kotagiri, A.G. Fitzmaurice, R. Lakshmanan, M.I. Ivanova, J.A. Loo,  F-G Klärner, T. Schrader, M. Stahl, G. Bitan, JM Bronstein. A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in vitro and in vivo.Neurotherapeutics.2011 9(2):464-76(* equal contribution)
7. Sinha, S, S. Cheng, C. Fan, T. Bobik. The PduM protein is a structural component of the microcompartments involved in coenzyme B12-dependent 1,2-propanediol degradation by Salmonella. J. Bacteriol.194(8):1912-8.
8. Sinha, S., D.H. Lopes, Z. Du, E.S. Pang, A. Shanmugam, A. Lomakin, P. Talbiersky, A. Tennstaedt, K. McDaniel, R. Bakshi, P.Y. Kuo, M. Ehrmann, G.B. Benedek, J.A. Loo, F.G. Klarner, T. Schrader, C. Wang, and G. Bitan, Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins. J. Am. Chem. Soc., 2011. 133(42): 16958-69.
9. Hochdorffer, K., J. Marz-Berberich, L. Nagel-Steger, M. Epple, W. Meyer-Zaika, A.H. Horn, H. Sticht, S. Sinha, G. Bitan, and T. Schrader, Rational design of beta-sheet ligands against Ab42-induced toxicity. J. Am. Chem. Soc., 2011. 133(12): 4348-58.
10. Cheng, S., S. Sinha, C. Fan, Y. Liu, and T.A. Bobik, Genetic analysis of the protein shell of the microcompartments involved in coenzyme B12-dependent 1,2-propanediol degradation by Salmonella. J. Bacteriol., 2011. 193(6): p. 1385-92
11. S. Sinha, Z. Du, P. Maiti, F.-G. Klärner, T. Schrader, C. Wang, and G. Bitan, Comparison of three amyloid assembly inhibitors – the sugar scyllo-inositol, the polyphenol epigallocatechingallate, and the molecular tweezers CLR01. ACS Chemical Neuroscience.2012 3 (6):451–458.
12. S. Prabhudesai,* S. Sinha*, A. Attar, A. Kotagiri, A.G. Fitzmaurice, R. Lakshmanan, M.I. Ivanova, J.A. Loo,  F-G Klärner, T. Schrader, M. Stahl, G. Bitan, JM Bronstein. A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in vitro and in vivo.Neurotherapeutics.2011 9(2):464-76(* equal contribution)
13. Surolia, I*., S. Sinha*, D.P. Sarkar, P.Y. Reddy, G.B. Reddy, and A. Surolia, Concurrence of Danish dementia and cataract: insights from the interactions of dementia associated peptides with eye lens alpha-crystallin. PLoS One, 2008.3(8): p. e2927. (*equal contribution)
14. Sinha, S. and A. Surolia, Attributes of glycosylation in the establishment of the unfolding pathway of soybean agglutinin. Biophys. J., 2007. 92(1): p. 208-16.
15. Sinha, S., G. Gupta, M. Vijayan, and A. Surolia, Subunit assembly of plant lectins. Curr. Opin. Struct. Biol., 2007.17(5): p. 498-505.
16. Sinha, S. and A. Surolia, Oligomerization endows enormous stability to soybean agglutinin: a comparison of the stability of monomer and tetramer of soybean agglutinin. Biophys. J., 2005. 88(6): p. 4243-51.
17. Sinha, S., N. Mitra, G. Kumar, K. Bajaj, and A. Surolia, Unfolding studies on soybean agglutinin and concanavalin a tetramers: a comparative account. Biophys. J., 2005. 88(2): p. 1300-10.
Book Chapters:
♦ Amyloids and Protein Aggregation—Analytical Methods.   Li H, F Rahimi, K Murakami, SSinha, P Maiti, G Bitan.Encyclopedia of Analytical Chemistry. 2009
♦ Application of Photochemical Cross-linking to the Study of Oligomerization of Amyloidogenic Proteins. Lopes DHJ, S Sinha, C Rosensweig, G Bitan. Methods Mol Biol. 849:11-21.2012

Causes Sharmistha cares about:

Positions held at Padakshep:
Core group member and volunteer. 
Sharmistha Sinha-Rakshit has been a part of Padakshep since its inception. She has also been guiding Sanjoy Mohanta since 2010......https://sites.google.com/a/padakshep.org/padakshep-members/past-volunteers/sharmistha-sinha-rakshit













MOHALI, Chandigarh, India
Map of Ajitgarh, Punjab













BURDWAN, INDIA

Map of burdwan city






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