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Friday 11 December 2015

Upendra Sharma



image file: BK9781849738965-FP021-u28.tif 

Upendra Sharma


PhD
Scientist
, Pālampur · Natural Product Chemistry and Process Development Division (NPC & PDD)

Upendra Sharma studied chemistry at Guru NankDev University, Amritsar (India) until 2005, and subsequently obtained a PhD degree in organic chemistry with Dr Bikram Singh, Chief Scientist, CSIR–IHBT, Palampur. In the fall of 2012, he joined Prof. D. Maiti at IIT Bombay as Young Scientist. His research interests involve metal-catalyzed selective C–H activation and natural product synthesis.\




 

Research Experience

  • Sep 2014–
    present
    Scientist
    CSIR - Institute of Himalayan Bioresource Technology · Natural Product Chemistry and Process Development Division · http://www.ihbt.res.in/php/cv/sctInfo.php?id=34049
    India · Pālampur
    We work on C-H Activation and Phytochemistry
  • Mar 2014–
    Aug 2014
    PostDoc Position
    Korea Advanced Institute of Science and Technology
    South Korea · Seoul
    Worked on remote C-H activation
  • Nov 2012–
    Mar 2014
    PostDoc Position
    Indian Institute of Technology Bombay · Department of Chemistry · catalysis
    India · Mumbai
    Worked on C-H activation/functionalisation
  • Jan 2007–
    Oct 2012
    Ph.D
    CSIR - Institute of Himalayan Bioresource Technology · Natural Plant Products Research Area (IHBT)
    India · Palampur
    Worked in Phytochemistry and catalysis with metal phthalocyanine
  • Nov 2005–
    Oct 2006
    Research Scholar
    Panjab University · Department of Chemistry · Raj Pal Sharma
    India · Chandigarh
    Worked on synthesis and characterization of metal complexes

Contact Details

     
Name Dr. Upendra Sharma
Designation Scientist
Division Natural Product Chemistry and Process Development
Ph. (+91)9418792595
E-mail upendra@ihbt.res.in
Specialization Transition Metal Catalysis and Phytochemistry
     

Research

 
Please visit; https://sites.google.com/site/chactivationandphytochemistry/home


After Independent Research Lab

2015

56. R. Sharma, R. Kumar, I. Kumar, U. Sharma* Rh(III)-Catalyzed Dehydrogenative Coupling of Quinoline N-Oxides with Alkenes: N-Oxide as Traceless Directing Group for Remote C-H Activation. European Journal of Organic Chemistry 2015, accepted.

55. R. Sharma, R. Kumar, I. Kumar, B. Singh and U. Sharma* Selective C-Si Bond Formation through C-H Functionalization. Synthesis, 2015, 47(16), 2347-2366.

54. R. Sharma, K. Thakur, R. Kumar, I. Kumar and U. Sharma* Distant C-H Activation/Functionalization: A New Horizon of Selectivity beyond Proximity. Catalysis Reviews: Science and Engineering, 2015, 57(3), 345-405.

53. K. Thakur, R. Sharma and U Sharma* Olefins as Unprecedented Feedstock for the Synthesis of Valuable Heterocycles: Regioselectivity Remains an Issue. Synlett, 2015, 26(02), 137-141.

52. R. Rattan,* S. G. E. Reddy, S. K. Dolma, B. I. Fozdar, V. Gautam, R. Sharma, U. Sharma* Triterpenoid Saponins from Clematis graveolens and Evaluation of their Insecticidal Activities. Natural Product Communications, 2015, 10(9), 1525-1528.

51. Dinesh Kumar*, Ashu Gulati, Upendra Sharma*. Determination of Theanine and Catechin in Camellia sinensis (Kangra Tea) Leaves by HPTLC and NMR Techniques. Food Analytical Methods, 2015, accepted


Before Independent Research Lab


2015

50. S. Agasti, U. Sharma, T. Naveen, and D. Maiti. Orthogonal Selectivity with Cinnamic Acids in 3-substituted Benzofuran Synthesis through C–H Olefination of Phenols. Chemical Communication, 2015, 51, 5375-5378.

2014

49. U. Sharma, Rajesh Kancherla N. Tagoti, Soumitra Agasti and D. Maiti. Palladium-Catalyzed Annulation of Diarylamines with Olefins through C–H Activation: Direct Access to N-Arylindoles. Angewandte Chemie International Edition, 2014, 53, 11895.

Highlighted in Synfacts 2015, DOI: 10.1055/s-0034-1379706

48. U. Sharma, Y. Park , and S. Chang. Rh(III)-Catalyzed Traceless Coupling of Quinoline N-Oxides with Internal Diarylalkynes. Journal of Organic Chemistry, 2014, 79, 9899-9906.

47. M. Walia, U. Sharma, V. Agnihotri and B. Singh. Silica-Supported Boric Acid Assisted Conversion of Mono- and Poly-saccharides to 5-Hydroxymethylfurfural in Ionic Liquid. RSC Advance, 2014, 4, 14414.

46. S. Maiti, N. Tagoti, U. Sharma and D. Maiti. Efficient and Stereoselective Nitration of Olefins with AgNO2 and TEMPO. Synlett, 2014, 25, 603. (Invited Synpact article)

45. P. K. Verma, M. Bala, K. Thakur, U. Sharma, N. Kumar and B. Singh. Iron and Palladium (II) Phthalocyanines as Recyclable Catalysts for Reduction of Nitroarenes. Catalysis Letter, 2014, 144, 1258.

44. A. Chaudhary, U. Sharma, A. P. Vig, B. Singh, S. Arora. Free radical scavenging, antiproliferative activities and profiling of variations in the level of phytochemicals in different parts of broccoli (Brassica oleracea italica). Food Chemistry, 2014, 148, 373.

43. V. Kumar, C. Singh, U. Sharma, P. K. Verma, B. Singh and N. Kumar. Silica-supported Boric Acid Catalyzed Synthesis of Dihydropyrimidin-2-ones, Bis(indolyl)methanes, Esters and Amides. Indian Journal of Chemistry Section –B, 2014, 53B, 83.

2013

42. U. Sharma, N. Tagoti, A. Maji, S. Manna and D. Maiti. Palladium Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins. Angewandte Chemie International Edition. 2013, 52, 12669.(Most Accessed Paper in October, 2013)

41. S. Maiti, N. Tagoti, U. Sharma and D. Maiti. Stereoselective Nitration of Olefins with tBuONO and TEMPO: Direct Access to Nitroolefins under Metal-free Condition. Organic Letter, 2013, 15, 3384.(Highlighted by Organic Chemistry Portal 2013;
http://www.organic-chemistry.org/abstracts/lit4/087.shtm)

40. N. Tagoti, S. Maiti, U. Sharma and D. Maiti. A Predictably Selective Nitration of Olefin with Fe(NO3)3 and TEMPO. Journal of Organic Chemistry, 2013, 78, 5949.(Highlighted in Organic Process Research & Development 2013, 17, 1076−1084; Highlighted by Organic Chemistry Portal 2013;http://www.organic-chemistry.org/abstracts/lit4/062.shtm)

39. T. Patra, A. Deb, S. Manna, U. Sharma and D. Maiti. Iron-Mediated Decarboxylative Trifluoromethylation of α,β-Unsaturated Carboxylic Acids with Trifluoromethanesulfinate. European Journal of Organic Chemistry, 2013, 24, 5257.(Highlighted in Organic Process Research & Development 2013, 17, 1369-1379)

38. M. Bala, P. K. Verma, U. Sharma, N. Kumar and B. Singh. Iron Phthalocyanine as an Efficient and Versatile Catalyst for N-alkylation of Heterocyclic Amines with Alcohols: One-pot Synthesis of 2-Substituted Benzimidazoles, Benzothiazoles and Benzoxazoles. Green Chemistry 2013, 15, 1687.

37. S. Nagarajan, S. Majumder, U. Sharma, S. Rajendran, N. Kumar, S. Chatterjee, B. Singh. Synthesis and anti-angiogenic activity of benzothiazole, benzimidazole containing phthalimide derivatives. Bioorganic Medicinal Chemistry Letters, 2013, 13, 287.

36. P. K. Verma, U. Sharma, M. Bala, N. Kumar and B. Singh. Transition Metal-free 1,3-Dimethylimidazolium Hydrogen Carbonate Catalyzed Hydration of Organonitriles to Amides. RSC Advance, 2013, 3, 895.

35. M. Kumar, U. Sharma, S. Sharma, V. Kumar, B. Singh and N. Kumar Catalyst-Free Water Mediated Reduction of Nitroarenes Using Glucose as Hydrogen Source. RSC Advance, 2013, 3, 4894.

34. M. Bala, P. K. Verma, N. Kumar, U. Sharma, and B. Singh. Highly Efficient Iron Phthalocyanine Catalysed Oxidative Synthesis of Imines from Alcohols and Amines. Canadian Journal of Chemistry, 2013, 91, 732.(Most downloaded articles of the from May to November, 2013)

33. P. K. Verma, N. Kumar, U. Sharma, M. Bala, V. Kumar and B. Singh. Transition Metal-Free Sodium Borohydride Promoted Controlled Hydration Of Nitriles To Amides. Synthetic Communication, 2013, 43, 2867.

32. U. Sharma, N. Kumar, B. Singh, R. K. Munshi and S. Bhalerao. Immunomodulatory Active Steroidal Saponins from Asparagus racemosus. Medicinal Chemistry Research, 2013, 22, 573.

31. D. Katoch, D. Kumar, U. Sharma, N. Kumar, Yogendra S. Padwad, Brij Lal and B. Singh. Zephgrabetaine: A New Betaine-type Amaryllidaceae Alkaloid from Zephyranthes grandiflora. Natural Product Communications, 2013, 8, 161-164.

30. M. Walia, U. Sharma, S. Bhushan, N. Kumar and B. Singh. Arabinan-type Polysaccharides from Industrial Waste Apple Pomace. Chemistry of Natural compounds, 2013, 49, 794.

29. U. Sharma, D. Katoch, S. Sood, N. Kumar, B. Singh, Archana Thakur and Arvind Gulati. Synthesis, Antibacterial and Antifungal activity of 2-Amino-1, 4-Naphthoquinones Using Silica-Supported Perchloric Acid (HClO4-SiO2) as a Mild, Recyclable and Highly Efficient Heterogeneous Catalyst. Indian Journal of Chemistry Section –B, 2013, 52B, 1431.

28. C. Singh, V. Kumar, U. Sharma, N. Kumar and B. Singh. Recent Advances in the Synthesis of Amide. Current Organic Synthesis, 2013, 10, 241.

2012

27. U. Sharma, N. Kumar, P. K. Verma, V. Kumar and B. Singh. Zinc Phthalocyanine with PEG-400 as A Recyclable Catalytic System for Selective Reduction of Aromatic Nitro Compounds. Green Chemistry 2012, 14, 2289.

26. U. Sharma, M. Bala, N. Kumar, B. Singh, R. K. Munshi and S. Bhalerao. Immunomodulatory Active Compounds from Tinospora cordifolia. Journal of Ethnopharmacology, 2012, 141, 918.

25. U. Sharma, M. Bala, R. Saini, P. K. Verma, N. Kumar, B. Singh, R. K. Munshi and S. Bhalerao. Polysaccharide Enriched Immunomodulatory Fractions from Tinospora cordifolia. Indian Journal of Experimental Biology, 2012, 50, 612.

24. U. Sharma, N. Kumar and B. Singh New Furostanol Saponin and Phenyl Propanoid from Roots of Asparagus racemosus. Natural Product Communications 2012, 7, 995-998.

23. V. Kumar, S. Sharma, U. Sharma, B. Singh and N. Kumar. Synthesis of Substituted Amines and Isoindolinones: Catalytic Reductive Amination using Abundantly Available AlCl3/PMHS. Green Chemistry 2012, 14, 3410.

22. V. Kumar, U. Sharma, P. K. Verma, N. Kumar and B. Singh. Cobalt(II) Phthalocyanine Catalyzed Highly Chemoselective Reductive Amination of Carbonyl Compounds in a Green Solvent. Advanced Synthesis & Catalysis, 2012, 354, 870.

21. A. Chaudhary, G. Rampal, U. Sharma, T. S. Thind, B. Singh, A. P. Vig, and S. Arora. Anticancer, antioxidant activities and GC-MS analysis of glucosinolates in two cultivars of broccoli. Medicinal Chemistry & Drug Discovery 2012, 2, 30.

20. M. Chandel, U. Sharma, N. Kumar, B. Singh and S. Kaur. Antioxidant Activity and Identification of Bioactive Compounds from Leaves of Anthocephalus cadamba by Ultra-Performance Liquid Chromatography/Electrospray Ionization Quadrupole Time of Flight Mass Spectrometry. Asian Pacific Journal of Tropical Medicine, 2012, 977.

19. V. Kumar, U. Sharma, B. Singh and N. Kumar. Direct One-Pot Cobalt(II) Phthalocyanine Catalyzed Synthesis of N-Substituted Isoindolinones. Australian Journal of Chemistry, 2012, 65, 1594.

18. P. K. Verma, U. Sharma, N. Kumar, M. Bala, V. Kumar and B. Singh. Nickel Phthalocyanine Assisted Highly Efficient and Selective Carbonyl Reduction in Polyethylene Glycol-400. Catalysis Letter, 2012, 142, 907.

17. N. Kumar, U. Sharma, C. Singh and B. Singh. Thalidomide: Chemistry, Therapeutic Potential and Oxidative Stress Induced Teratogenicity. Current Topics in Medicinal Chemistry, 2012, 12, 1436.

2011

16. U. Sharma, P. K. Verma, N. Kumar, V. Kumar, M. Bala and B. Singh. Phosphane-Free Green Protocol for Selective Nitro Reduction with Iron Based Catalyst. Chemistry: A European Journal, 2011, 17, 5903.

15. V. Kumar, U. Sharma, P. K., N. Kumar and B. Singh. Silica-Supported Boric Acid with Ionic Liquid: A Recyclable and Green Catalytic System for One-Pot Three-Component Mannich Reaction. Chemical & Pharmaceutical Bulletin, 2011, 59, 639.

14. R. Kaur, U. Sharma B. Singh and S. Arora. Antimutagenic and Antioxidant Characteristics of Chukrasia tabularis A. Juss. Extracts. International Journal of Toxicology, 2011, 30, 21.

13. R. Kaur, U. Sharma, B. Singh and S. Arora. Antimutagenic Potential of Chickrassy (Chukrasia tabularis A. Juss) bark. Journal of Medicinal Plants Research, 2011, 5, 5021.

2010

12. U. Sharma, P. K., N. Kumar, V. Kumar and B. Singh. Highly Chemo- and Regioselective Reduction of Aromatic Nitro Compounds Catalyzed by Recyclable Copper(II) as well as Cobalt(II) Phthalocyanine. Advanced Synthesis & Catalysis, 2010, 352, 1834.

11. U. Sharma, P. K., N. Kumar and B. Singh. Recent Developments in the Chemistry of Phthalimide Derivatives and Their Role as TNF-α Inhibitor. Mini Review in Medicinal Chemistry, 2010, 10, 678.

10. U. Sharma, P. Bhandari, N. Kumar and B. Singh. Simultaneous Determination of Ten Sugars in Tinospora cordifolia by Ultrasonic Assisted Extraction and HPLC-ELSD Method. Chromatographia, 2010, 71, 633.

9. U. Sharma, M. Bala, P. K., G. Rampal, N. Kumar, B. Singh, and S. Arora. Antimutagenic Extract from Tinospora cordifolia and its Chemical Composition. Journal of Medicinal Plants Research, 2010, 4, 2488.

2009

8. U. Sharma. Silica Supported Perchloric Acid (HClO4-SiO2): A Versatile Reagent in Organic Synthesis. Synlett, No. 2009, 19, 3219.

7. U. Sharma, R. Saini, Bobita, N. Kumar and B. Singh. Steroidal Saponins from Asparagus racemosus. Chemical & Pharmaceutical Bulletin, 2009, 57, 890.

2007

6. R. Bala, R. P. Sharma, U. Sharma, Andrew D. Burrows and Kevin Cassar. Hexaamminecobalt(III) Complexes as Multiple Hydrogen Bond Donors: Synthesis, Characterization and X-ray Structural Study of Mixed Anion Complexes [Co(NH3)6]Br2(BF4) and [Co(NH3)6]Cl2(HC2O4).H2O. Journal of Molecular Structure, 2007, 832, 156.

2006

5. R. Bala, R. P. Sharma, U. Sharma and V. Ferretti. The First X-ray Structure of a Hexaamminecobalt(III) Salt with Two Different Complex Chlorocadmium Anions: Synthesis, Characterization and Crystal Structure of [Co(NH3)6]4[CdCl6][CdCl4(SCN)(H2O)]2Cl2.2H2O. Acta crystallographica. Section C, 2006, 62, m 628.


Book Chapter

4. U. Sharma, A. Modak, S. Maity, A. Maji and D. Maiti. Direct Arylation via C-H activation. Thomas CoIacot eds., Introduction to New Trends in Cross-Coupling: Theory and Applications. 2014.

3. M. Chandel, U. Sharma, N. Kumar, B. Singh and S. Kaur. In Vitro Studies on the Antioxidant/Antigenotoxic Potential of Aqueous Fraction from Anthocephalus cadamba Bark. P.R. Sudhakaran et al. (eds.), Perspectives in Cancer Prevention-Translational Cancer Research, 2013, DOI 10.1007/978-81-322-1533-25.

Patent

2. B. Singh, S. Chattergi, N. Kumar and U. Sharma. Benzothiazole Substituted Phthalimide Analogues as Potential Angiogenesis Inhibitors. Ref. No. 0918 DEL 2011.

1. U. Sharma, N. Tagoti, and D. Maiti. Palladium-Catalyzed Synthesis of Benzofurans and Coumarins from Phenols and Olefins. Status: Provisional. IPA No: 2012/Mum/2013.



     

Awards and Recognitions

 
CSIR-NET (2006)
GATE (2007)
CSIR Junior Research Fellowship (2007)
CSIR Senior Research Fellowship (2009)
Foreign Travel Grant by DST-New Delhi and CSIR-New Delhi
Fast Track Young Scientist Project (2012)
D S Kothari Postdoc Fellowship (2012)
IBS Postdoc Fellowship, KAIST, South Korea (2014)
     

Team

 
Ms. Ritika Sharma, Ph.D Student
Mr. Rakesh Kumar, Ph.D Student
Mr. Inder Kumar, Ph.D Student

Prospective Team Members

Ph.D and Postdoc positions available for self motivated persons.



Carin C. C. Johansson Seechurn



image file: BK9781849738965-FP021-u27.tif 

 Carin C. C. Johansson Seechurn

Carin Johansson Seechurn completed her MChem with French degree at UMIST (University of Manchester Institute of Science and Technology) in 2003. This included a year abroad at CPE (l’Ecole Supérieure Chimie, Physique, Electronique de Lyon) in France. From 2003 until 2007 she carried out PhD studies at the University of Cambridge, under the supervision of Prof. Matthew Gaunt. Her PhD work focused on the development of novel organocatalytic methodology. After the completion of the PhD studies, she continued to work for Prof. Gaunt, now in the area of palladium catalysis. In 2008 she joined the Catalysis and Chiral Technologies Division of Johnson Matthey in Royston, UK, where she is working on the development of novel homogeneous metal catalysts.

David A. Petrone



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 David A. Petrone

David A. Petrone was born in Ontario, Canada, in 1989. He obtained his BSc degree with Honors in Chemistry in 2011 from the University of Guelph under the supervision of Prof. Kathryn Preuss and Prof. William Tam. He is currently a PhD student in Mark Lautens’ research laboratory at the University of Toronto, where he is studying Pd(0)-catalyzed carbohalogenation reactions.

Steven P. Nolan



image file: BK9781849738965-FP021-u25.tif 

 Steven P. Nolan

Steven P. Nolan received his BSc in Chemistry from the University of West Florida and his PhD from the University of Miami where he worked under the supervision of Prof. Carl D. Hoff. After a postdoctoral stay with Prof. Tobin J. Marks at Northwestern University, he joined the Department of Chemistry of the University of New Orleans in 1990. In 2006 he joined the Institute of Chemical Research of Catalonia (ICIQ) as Group leader and ICREA Research Professor. In early 2009, he joined the School of Chemistry at the University of St Andrews where he holds the Chair in Inorganic Chemistry. His research interest include organometallic chemistry and homogeneous catalysis.

Timothy Noël



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 Timothy Noël


Timothy Noël was born in Aalst, Belgium, and received an MSc degree (Industrial Chemical Engineering) from the KaHo Sint-Lieven in 2004. In 2009, he received his PhD at the University of Ghent with Prof. Johan Van der Eycken (Department of Organic Chemistry). He then moved to Massachusetts Institute of Technology as a Fulbright Postdoctoral Fellow with Prof. Stephen L. Buchwald (Department of Chemistry), where he worked on flow chemistry (MIT–Novartis Center for Continuous Manufacturing). In 2012, he accepted a position as Assistant Professor at Eindhoven University of Technology, The Netherlands. In 2011, Dr Noël received an Incentive Award for Young Researchers from the Comité de Gestion du Bulletin des Sociétés Chimiques Belges. In 2012, he received a prestigious VENI Award from the Dutch Government (NWO). He is also Associate Editor of the Journal of Flow Chemistry. His research interests are focused on the combination of flow chemistry, organic synthetic chemistry and catalysis.

Stephen G. Newman



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 Stephen G. Newman

Stephen G. Newman was born in Newfoundland, Canada in 1985. He obtained a BSc degree with a major in chemistry from Dalhousie University in 2008. In 2012, he graduated with a PhD degree from the University of Toronto under the supervision of Prof. Mark Lautens. He is currently an NSERC Postdoctoral Fellow in the laboratory of Prof. Klavs F. Jensen, and will joining the faculty at the University of Ottawa in summer 2014 as an Assistant Professor of Chemistry.

Atanu Modak



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 Atanu Modak


Atanu Modak was born in 1989 in West Bengal (India). He graduated from Ramakrishna Mission Vidyamandira, Belur, with a BSc degree in chemistry from the University of Calcutta in 2009. He then pursued an MSc degree in chemistry at the Indian Institute of Technology, Kanpur, in 2011. From January 2012 he has been working as a PhD student in Prof. D. Maiti’s laboratories at IIT Bombay.

Arun Maji


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Arun Maji



Arun Maji was born in 1989 in Durgapur, West Bengal (India). He completed his graduation from Presidency College (Kolkata) and received his BSc degree in 2010. After completing his MSc degree at the Indian Institute of Technology, Kanpur, he joined Prof. Maiti’s group in 2012, where he has completed his first year of PhD studies.

Soham Maity



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 Soham Maity


Soham Maity was born in 1988 in West Bengal (India). He studied chemistry at St Xavier’s College, Kolkata, and received his BSc degree in 2009. After completing his MSc degree at the University of Calcutta he joined Prof. D. Maiti’s group in 2011, where he is currently a third-year PhD student.

Debabrata Maiti



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 Debabrata Maiti


Debabrata Maiti received his PhD from Johns Hopkins University (USA) in 2008 under the supervision of Prof. Kenneth D. Karlin. After postdoctoral studies at Massachusetts Institute of Technology (MIT) with Prof. Stephen L. Buchwald (2008–10), he joined the Department of Chemistry of IIT Bombay as an Assistant Professor in 2011. His research interests are focused on the development of new and sustainable synthetic methodologies.

Javier Magano



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 Javier Magano

Javier Magano was born in Madrid, Spain. He received a BS degree in organic chemistry from Complutense University in Madrid and an MS degree in chemistry from the University of Michigan. After working for the oil industry in Spain for several years, he obtained an MS degree in rubber and polymer science at the Center for Advanced Scientific Research in Madrid. After moving back to the USA, he joined the early process chemistry group at Pfizer in 1998 in Ann Arbor, MI, where he spent 9 years developing scalable processes for the preparation of drug candidates. In 2007, he moved to Groton, CT to continue his work as a process chemist and, during this period, he also worked in the area of biologics for 1½ years on the preparation of linkers for bioconjugation processes. Javier currently holds a position in the Chemical Technology group at Pfizer, where he is involved in the applications of high-throughput screening to transition metal-catalyzed cross-couplings. His research interests also include the development of catalytic processes that employ non-precious metals in cross-coupling reactions.

Guy Lloyd-Jones



image file: BK9781849738965-FP021-u17.tif 
 Guy Lloyd-Jones

Guy Lloyd-Jones studied at Huddersfield Polytechnic (BSc, 1989) and Oxford University (DPhil with John M. Brown FRS, 1992) before tenure of a Royal Society postdoctoral fellowship at the University of Basel with Andreas Pfaltz. He joined the University of Bristol in 1996 and was promoted to full Professor in 2003. In 2013 he was elected to the Royal Society (FRS) and moved to Edinburgh University as the Forbes Professor of Organic Chemistry.

Alastair Lennox



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 Alastair Lennox

Alastair Lennox is a graduate of Manchester University (2008, 1st class, MChem), where he conducted a final year research project with Dr Ian Watt and spent a year studying at the University of California, Los Angeles. He obtained his PhD in 2012 at the University of Bristol, where he worked under the supervision of Prof. Guy Lloyd-Jones and studied the reactivity of potassium organotrifluoroborate salts in Suzuki–Miyaura couplings.

Christine M. Le



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 Christine M. Le

Christine Le was born in 1989 in Canada and completed her BSc degree at Western University. She then moved to the University of Toronto and obtained her Master’s degree in the group of Prof. Vy Dong, where she carried out research in the field of Rh-catalyzed hydroacylation. She is currently pursuing her PhD at the University of Toronto under the supervision of Prof. Mark Lautens. Her research involves asymmetric transformations enabled by Rh and Pd catalysis.

Hongbo Li



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 Hongbo Li

Hongbo Li completed his both BS and MS in Chemistry at Peking University, China before he moved to the USA in 2000. He completed his PhD at Northwestern University under the supervision of Prof. Tobin Marks in 2005. His PhD work focused on the development of novel olefin polymerization catalysts. After working briefly at IBM Almaden Research Center, in 2006 he joined Los Alamos National Laboratory as Research Associate, where he worked on the development of immobilized catalysts. In 2008, he joined the Catalysis and Chiral Technologies Division of Johnson Matthey in West Deptford, NJ, where he is working on the development of novel homogeneous organometallic catalysts.

Mark Lautens



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 Mark Lautens

Mark Lautens was born in Ontario, Canada. He obtained his BSc degree from the University of Guelph, where he graduated with distinction. He conducted his doctoral studies at the University of Wisconsin-Madison under the direction of Barry M. Trost, where he discovered Mo-catalyzed allylic alkylation and Pd enyne cycloisomerization. In 1985, he moved to Harvard University where he conducted his NSERC PDF with David A. Evans on studies directed toward the synthesis of bryostatin, a potent anti-cancer agent. He joined the University of Toronto in 1987 as an NSERC University Research Fellow and Assistant Professor. He was promoted to Associate Professor in 1992 and Professor in 1995. Since 1998, he has held an Endowed Chair, the AstraZeneca Professor of Organic Synthesis, and from 2003–13 he was named an NSERC/Merck Frosst Industrial Research Chair in New Medicinal Agents via Catalytic Reactions. In 2012, he was appointed as University Professor, the highest rank at the University of Toronto.

Kazunori Koide



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 Kazunori Koide

Professor Koide obtained his bachelor’s and master’s degrees from the Department of Pharmaceutical Sciences at the University of Tokyo, Japan, where he developed new glycosylation methods in the Ohno group. He then moved to the United States and received a PhD in chemistry at the University of California, San Diego, under the guidance of Professor K. C. Nicolaou. As a Merck Fellow of Cancer Research Fund of the Damon Runyon-Walter Winchell Foundation, he conducted post-doctoral research with Professor Gregory L. Verdine in the Department of Chemistry and Chemical Biology at Harvard University. He then began his independent academic career in the Department of Chemistry at the University of Pittsburgh. His current research interests include development of new synthetic methods, total synthesis of biologically important natural products, chemical biology and medicinal chemistry of natural products, and development and applications of fluorescent chemosensors and chemodosimeters.

Eric C. Keske



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 Eric C. Keske

Eric Keske was born in London, ON, Canada. He obtained his BSc at the University of Western Ontario in 2009 and then moved to Queen’s University to pursue a PhD in organometallic chemistry with Prof. Cathleen Crudden. During this time he enjoyed short research stays with Dr Eric Fillion at the University of Waterloo and Dr Martin Albrecht at University College Dublin. Eric’s research interests involve late transition metal catalysis and reaction discovery. Eric considers himself a bourbon connoisseur, and can easily be distracted from the laboratory by loud music, whiskey and judo practice.

Ben W. Glasspoole



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 Ben W. Glasspoole

Ben Glasspoole was raised in Montreal, Quebec and completed his BSc at McGill University in 2006. He then completed his PhD under the guidance of Prof. Cathleen Crudden at Queen’s University, Kingston, ON, Canada in 2011, working in the field of Pd catalysis. During his PhD term he carried out a research exchange with Prof. Varinder Aggarwal. After performing postdoctoral work with Prof. Michael Krische at the University of Texas at Austin, Ben joined Sigma-Aldrich in 2013.

Joshua R. Dunetz



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 Joshua R. Dunetz

Joshua R. Dunetz graduated from Haverford College, Haverford, PA in 2000 with a BA in Chemistry after undergraduate research with Prof. Karin Åkerfeldt. He received his PhD in Organic Chemistry from MIT in 2005 under the guidance of Prof. Rick Danheiser, and then completed postdoctoral studies with Prof. William Roush at the Scripps Research Institute, Jupiter, FL. In early 2008, Joshua joined Pfizer Chemical R&D, where he developed processes for the GMP manufacture of small molecules on the gram to multi-kilogram scale. After six wonderful years with Pfizer, Joshua relocated to California to join the Process Chemistry team at Gilead Sciences.

Andrew DeAngelis



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 Andrew DeAngelis


Andrew DeAngelis received his BS in Chemistry from Moravian College, Bethleham, PA, in 2005, where he conducted undergraduate research with Prof. Carl Salter. He then went on to earn his PhD in Chemistry and Biochemistry from the University of Delaware in 2011, where he worked on the development of new catalytic reactions with Rh-carbenoids under the guidance of Prof. Joseph M. Fox. He subsequently pursued postdoctoral studies with Prof. Stephen L. Buchwald at Massachusetts Institute of Technology, where he worked on the development of new cross-coupling processes in continuous flow. In 2012, he joined Johnson Matthey as a research scientist working in the Catalysis and Chiral Technologies Division in West Deptford, NJ, where he is engaged in the development and applications of novel homogeneous metal catalysts and also process development for scale-up.

Cathleen M. Crudden



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 Cathleen M. Crudden


Cathleen Crudden obtained her BSc and MSc from the University of Toronto with Dr Mark Lautens, and her PhD jointly with Dr Howard Alper at the University of Ottawa and Dr Shinji Murai at Osaka University, Japan. Following this, she took up an NSERC PDF with Prof. Scott Denmark at the University of Illinois at Urbana Champaign. She then became an Assistant Professor at the University of New Brunswick, where she was awarded a Research and Innovation Award and a UNB Merit Award, and received the first university Research Professorship. In 2002, she took up the position of Queen’s National Scholar at Queen’s University, Kingston, ON, Canada, where she was awarded a Premier’s Research and Excellence Award and a Chancellor’s Research Award. One of her publications was in the top 10 most cited papers of the year for all of science in Canada for the year 2006. In 2012 she was appointed Research Professor at the Institute of Transformative Bio-Molecules in Nagoya, Japan. She has won numerous research awards, including the Clara Benson Award for the top female chemist in Canada and an NSERC Accelerator Award. Her diverse research program includes materials chemistry, organic chemistry, catalysis and chirality. She has been a Visiting Professor at the Research Center for Materials Science in Nagoya University, in the laboratories of Prof. Ryoji Noyori (joint recipient of the Nobel Prize in Chemistry, 2001). In 2008, she was awarded a Global Center of Excellence Professorship at Kyoto University. She was also awarded a Visiting Professorship by the Catalan Government in Tarragona, Spain, in 2007. Cathleen was President of the Canadian Society for Chemistry (CSC) in 2012–13. Prior to becoming CSC President, she served on the Board of Directors for two terms representing the Catalysis Division. She also served on the Editorial Advisory Board for ACCN for 10 years. She has been a member of the organizing committee of Pacifichem for the past 7 years and served as area coordinator for materials and inorganic chemistry.

Andrei V. Cheprakov



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 Andrei V. Cheprakov

Andrei V. Cheprakov graduated from the Department of Chemistry of Moscow State University in 1983 and joined Prof. I. Beletskaya’s Laboratory of Organoelement Compounds. His PhD thesis was devoted to the oxidative halogenation of aromatic compounds and was defended in 1989. Currently he is a Docent at the Chair of Organic Chemistry of Moscow University. His research interests include the methodology of transition metal-catalyzed reactions, reactions in non-conventional aqueous microheterogeneous media, chemistry and applications of brassinosteroids, chemistry of π-extended porphyrinoids and fluorogenic oligopyrrolic ligands.

Anthony Chartoire



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 Anthony Chartoire

Anthony Chartoire received his MSc and PhD in organic and organometallic chemistry from the University of Nancy, where he worked under the supervision of Prof. Yves Fort until 2010. In 2011, he joined the group of Prof. Steven P. Nolan at the University of St Andrews, where he worked as a Postdoctoral Research Fellow until August 2013. He is currently a research scientist at Econic Technologies. His research interests include organic and organometallic chemistry and homogeneous catalysis.

Christopher F. J. Barnard


Christopher F. J. Barnard
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 Christopher F. J. Barnard


Dr Christopher F. J. Barnard has worked for Johnson Matthey for 35 years. His principal contributions have been to the development of platinum compounds as the active ingredients in anti-cancer drugs and in developing catalytic chemistry for synthesis in pharmaceutical applications. Palladium-based chemistries such as coupling and carbonylation have been areas of particular interest in recent years.

Irina P. Beletskaya


Irina P. Beletskaya
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Irina P. Beletskaya received her Diploma degree in 1955, her PhD degree in 1958 and her Doctor of Chemistry degree in 1963 from Moscow State University. The subject of the last degree was Electrophilic Substitution at Saturated Carbon. She became a Full Professor at Moscow State University in 1970, and in 1974 she became a Corresponding Member of the Academy of Sciences (USSR), of which she became a full member (Academician) in 1992. She is currently Head of the Laboratory of Organoelement Compounds, Department of Chemistry, Moscow State University. Irina Beletskaya is Chief Editor of the Russian Journal of Organic Chemistry. She was President of the Organic Chemistry Division of IUPAC from 1989 to 1991. She was a recipient of the Lomonosov Prize (1979), the Mendeleev Prize (1982), The Nesmeyanov Prize (1991), the Demidov Prize (2003) and the State Prize (2004). She is the author of more 600 articles and four monographs. Her current scientific interests are manifold, including transition metal catalysis and organocatalysis in organic synthesis, organometallic derivatives of lanthanides, carbanions and nucleophilic aromatic substitution, supramolecular chemistry, and many others.

Thomas J. Colacot

Thomas J. Colacot
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 Thomas J. Colacot


Dr Thomas John Colacot was born in Central Kerala, India. After finishing his PhD in Chemistry at IIT Madras with Prof. M.N.S. Rao in 1989, he moved to the University of Alabama at Birmingham for a combined teaching and post-doctoral research position in the area of Group III-V Chemistry with Prof. L. K. Krannich. In 1992, he became an Asst. Professor at Florida A & M University, while collaborating with Prof. Will Rees at Florida State University. Due to family commitments, he moved to Southern Methodist University, Dallas in 1993 to work with Professor N.S. Hosmane on an Advanced Technology Program/AMCO project. Although Prof. Hosmane and Dr Colacot did not have any previous experience in catalysis, Dr Hosmane gave him complete freedom to explore catalysis research using mixed carborane–cyclopentadiene complexes of early transition metals for the manufacture of plastics (olefin polymerization).
In 1995, Dr Colacot began his career at Johnson Matthey, USA, directing the homogeneous catalysis research group. With an extensive background in ligand technology obtained during his time at IIT Madras, Chennai and UAB, in conjunction with his studies in catalysis from SMU, Dr Colacot focused his research in the area of precious metal catalysis and has become an industrial expert in cross coupling.
Through his research, Dr Colacot and his group have generated highly active, practical palladium based cross coupling catalysts for applications in pharmaceutical, fine chemical and academic labs. Currently, Dr Colacot is the R&D Global Manager of Homogeneous Catalysis. He has given numerous invited and plenary lectures in many international conferences and acts as an external PhD thesis examiner to IITs and universities and a visiting professor in many universities. He has contributed several publications, patents, book chapters and reviews. He is a Fellow of the Royal Society of Chemistry and has obtained a MBA from Pennsylvania State University. He received Royal Society’s 2012 RSC Applied Catalysis Award and Medal for his “exceptional contributions” to Homogeneous Catalysis, particularly for making this technology accessible to industry and academia, and recently he has received the 2015 American Chemical Society Award for Industrial Chemistry in “recognition of his contributions and leadership in the development and commercialization of ligands and precatalysts for metal-catalyzed organic synthesis, particularly cross-couplings, for industrial and academic use and applications”. Dr Colacot has coauthored Chapters 1–3 of the book.



Biographies, in New Trends in Cross-Coupling: Theory and Applications, 2014, pp. P021-P036 DOI: 10.1039/9781782620259-FP021
eISBN:978-1-78262-025-9

Shinji Hasebe

Shinji Hasebe



Shinji Hasebe
Kyoto University, Japan
Professor,
PSE Lab., Department of Chemical Engineering
 

Message

Shinji Hasebe From Micro-Chemical Plants to Global Environmental Problems
Process Systems Engineering (PSE) is a research area where the systematic methodologies for realizing innovative production systems are investigated.
Our group covers all aspects of design, operation, control, planning, and logistics for process industries.

Office

Room 124, A4 building, Katsura Campus
  Tel: +81 75 383 2667
  Fax: +81 75 383 2657
  e-mail: hasebe [at] cheme [dot] kyoto-u [dot] ac [dot] jp

Address

Department of Chemical Engineering
Kyoto University, Katsura Campus
Nishikyo-ku, Kyoto 615-8510
Japan

 
Academic Qualifications
1984, Doctor of Engineering, Kyoto University
1978, Master of Engineering, Kyoto University
1976, Bachelor of Engineering, Kyoto University

Academic Employment
2003- Professor
Department of Chemical Engineering, Kyoto University
1993-2003. Associate Professor
Department of Chemical Engineering, Kyoto University
1989-1993. Lecturer
Department of Chemical Engineering, Kyoto University
1981-1989. Instructor
Department of Chemical Engineering, Kyoto University

Professional Membership
Member, The American Institute of Chemical Engineers
Member, The Society of Chemical Engineers, Japan
Board Member (2009.3 - )
Chairman of Division of Systems, Information and Simulation Technologies (2008.4 - 2010.3)
Member, The Institute of Systems, Control and Information Engineers (Japan)
Board Member (2008.5 - )
Member, The Operations Research Society of Japan
Member, The Society of Instrument and Control Engineers
Member, Society for Chemistry and Micro-Nano Systems, Japan
Member of Scheduling Society of Japan
President (2008.9 - )

Research Topics
Scheduling and Supply Chain Management
Synthesis of Ecological Processes
Synthesis of Distillation Systems for Energy Conservation
Optimal Design and Operation of Micro Chemical Plants
Dynamic Optimization of Chemical Processes


Research Topics

Scheduling and Supply Chain Management

Scheduling and Supply Chain Management
  • Modeling of global SCM problem
  • Production planning under uncertainties

Synthesis of Ecological Processes

  • Synthesis of sequential use system of waste materials
  • Synthesis of biomass supply chain

Synthesis of Distillation Systems for Energy Conservation

HIDiC
  • Design and control of internally heat-integrated distillation column
  • Synthesis of heat-integrated distillation system

Optimal Design and Operation of Micro Chemical Plants

Micro Chemical Plant
  • Development of shape optimization method of micro devices
  • Fault detection of numbering-up process

Dynamic Optimization of Chemical Processes (inactive)

  • Dynamic optimization of SOFC start-up operation








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Claude de Bellefon

Claude de Bellefon.



Claude de Bellefon, Ph.D.
Scientific Director,
University of Lyon, CNRS-CPE Lyon, France
 
N° de téléphone : +33 (0)4 72 43 17 54
https://fr.linkedin.com/in/claude-de-bellefon-28985510/en

 

 LGPC - Laboratoire de Génie des Procédés Catalytiques

 Claude received his PhD in 1985 from the University of Strasbourg in the field of organometallic chemistry. The topic of his PhD thesis was the synthesis of heteropolymetallic molecular clusters. During a postdoc at Pennstate University, he synthesised polynuclear Ta organometallic oxide complexes. In 1987, he was awarded a permanent research position with the Centre National de Recherche Scientifique (CNRS) in Strasbourg. After further four years working in cluster chemistry and research on organometallic oxorhenium complexes at the Technical University Munich, he moved in 1991 to Rhône-Poulenc now Solvay, Lyon, to work on the catalytic hydrogenation of adiponitrile and other hydrogenation processes and reactors. In 1995, Claude moved back to the CNRS where he currently holds a position as Research Director and leads the group on “Catalytic Reactors Engineering” at the University of Lyon. In 1996, he received the Habilitation from the University of Lyon.

His main research interest covers process intensification - micro- and meso-structured catalytic reactors for pharmaceuticals, chemicals and energy - catalytic hydrogenations & oxidations - photocatalytic reactors - batch-to-continuous processes – homogeneous & heterogeneous catalysis – and flow-chemistry. Claude has authored more than 100 scientific peer-reviewed papers and book chapters, holds several patents, has given more than 50 invited lectures in international meetings and private or academic institutions, has advised more than 20 PhD works and co-organised several international meeting series such as CAMURE, EUROPACAT and IMRET. He teaches Master degree courses on “Catalytic Reaction Engineering” and “Kinetics and Catalysis”. Claude also serves as a member of the Editorial Boards of the Chemical Engineering Journal and the Journal of Flow Chemistry. He is currently the Scientific Director of CPE Lyon, the school for chemistry and chemical engineering of the University of Lyon.


Experience

Director

CNRS-LGPC
– Present (12 years)Lyon, France

Research director

CNRS - Centre national de la recherche scientifique
– Present (29 years 4 months)

Research associate

Rhone-Poulenc
(4 years 1 month)

Post-doc fellow

TU München
(1 year 2 months)
Projets



Education

Université de Strasbourg

Doctorat


 Claude de Bellefon Image


Publications

  • L. Vanoye, M. Pablos, N. Smith, C. de Bellefon, A. Favre-Réguillon.

    Aerobic oxidation of aldehydes : selectivity improvement using sequential pulse experimentation in continuous flow microreactor.

    RSC Advances 2014, 4, 57159–57163.
  • J.-N. Tourvieille, R. Philippe, C. de Bellefon

    Milli-Channel with Metal Foams Submitted to a Gas-Liquid Periodic Flow : External Mass Transfer Performances and Pressure Drop.

    Chem. Eng. J. 2015, 267, 332-346.
  • J.-N. Tourvieille, R. Philippe, C. de Bellefon

    Milli-Channel with Metal Foams Submitted to a Gas-Liquid Periodic Flow : Flow patterns, residence time distribution and pulsing properties.

    Chem. Eng.Sci. 2015, 126, 406-426.
  • L. Vanoye, M. Pablos, C. de Bellefon, A. Favre-Réguillon.

    Gas-liquid segmented flow microfluidics for screening copper/TEMPO-catalyzed aerobic oxidation of primary alcohols.

    Adv. Synth. Catal. 2015, 357, 739-746.
  • A.-K. Liedtke, F. Scheiff, F. Bornette, R. Philippe, D. W. Agar, C. de Bellefon

    Liquid–Solid Mass Transfer for Microchannel Suspension Catalysis in Gas–Liquid and Liquid–Liquid Segmented Flow.

    Ind. Eng. Chem. Res. 2015, 54, 4699-4708.
  • T. Galeandro-Diamant, M.-L. Zanota, R. Sayah, L. Veyre, C. Nikitine, C. de Bellefon, S. Marrot, V. Meille, C. Thieuleux

    Platinum nanoparticles in suspension are as efficient as Karstedt’s complex for alkene hydrosilylation

    Chem. Commun. 2015
  • Florica Simescu-Lazar, Valerie Meille, Frederic Bornette, Fabrice Campoli, Claude de Bellefon

    In situ electrochemical regeneration of deactivated coated catalyst on basket foam in {Robinson-Mahoney} reactor : Example of Pd/C for nitrobenzene hydrogenation

    Catal. Today 249, 52-58 (2015)
  • Rebecca E O’Neill, Laurent Vanoye, Claude De Bellefon, Farid Aiouache.

    Aldol-condensation of furfural by activated dolomite catalyst

    Applied Catalysis B : Environmental 144, 46-56, 2014
  • J. Leveque, R. Philippe, M.-L. Zanota, V. Meille, F. Sarrazin, L. Baussaron, C. de Bellefon

    Characterizations of a catalytic solid foam reactor for co-current gas-liquid upflow

    Récents progrès en Génie des procédés 2013
  • L. Vanoye, A. Favre-Réguillon, A. Aloui, R. Philippe, C. de Bellefon

    Insights in the Aerobic Oxidation of Aldehydes

    RSC Advances 2013



 

 

 
 

 




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