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Monday 15 August 2016

Dr.Gowravaram Sabitha

  • Prof. Gowravaram Sabitha (CSIR-Indian Institute of Chemical Technology, Hyderabad, India)
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Sabitha Gowravaram

Sabitha Gowravaram


Senior Principal Scientist at Indian Institute of Chemical Technology

Dr. Gowravaram Sabitha
AddressScientist, Organic Division I, Indian Institute of Chemical Technology, Hyderabad-500 007, India
Phone number+91-40-27160512
Fax number+91-40-27160512
CountryIndia
Keywords
  • Custom synthesis
  • New chemical entities
  • New methodologies
  • Synthetic organic chemistry
  • Total synthesis of natutral products

Links


Total Stereoselective Synthesis and Structural Revision of a γ-Lactone Polyketide of Fungal Origin

Gowravaram Sabitha reports the stereoselective synthesis and structural revision of a γ-lactone polyketide of fungal origin.
Stereoselective Synthesis of the Revised Structure of γ-Lactone Polyketide from Diaporthe sp. SXZ-19 and Its C-8 Epimer: K. S. N. Reddy, A. Y. Reddy, G. Sabitha
Synthesis 201648, DOI: 10.1055/s-0035-1561463
A recently described γ-lactone polyketide originally isolated from the fungal strain Diaporthe sp. SXZ-19 of Camptotheca acuminata and its C-8 epimer were synthesized in stereoselective manner and their structure revised by Professor Gowravaram Sabitha and her colleagues from the CSIR-Indian Institute of Chemical Technology (Hyderabad, India).
  • Revised structures of polyketide γ-lactone and its C-8 epimer
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Professor Reddy – one of the article’s co-authors – said: “Synthesis of a γ-lactone polyketide has been achieved by utilizing Carreira, Ohira–Bestmann and alkyne–aldehyde coupling reactions.” 



LIST OF PUBLICATIONS 1. Synthesis of the C1-C25 Southern Domain of Spirastrellolides B and F. Gowravaram Sabitha,* Allu Senkara Rao and J. S. Yadav. Org & Biomol. Chem. 2013, 11, 7218-7231. 
2. Stereoselective formal synthesis of aspergillide A. Gowravaram Sabitha,* D. Vasudeva Reddy, Allu Senkara Rao and J. S. Yadav. Tetrahedron Lett. 2010, 51, 4195–4198. 
3. The First Stereoselective Total Synthesis of (−)-Synrotolide. Gowravaram Sabitha,* Allu Senkara Rao, AnkiReddy Sandeep and Jhillu S. Yadav. Eur. J. Org. Chem. 2013, accepted. 
4. Stereoselective synthesis of (−)-synparvolide B. Gowravaram Sabitha,* Allu Senkara Rao and J. S. Yadav. Tetrahedron: Asymmetry 2011, 22, 866-871. 
5. The First Total Synthesis of (−)-Synparvolide C. Gowravaram Sabitha,* AnkiReddy Sandeep, Allu Senkara Rao and J. S. Yadav. Eur. J. Org. Chem. 2013, accepted. 
6. Synthesis of the C1-C13 Subunit of Spirastrellolide A and B by Prins Cyclization. Gowravaram Sabitha,* Allu Senkara Rao and J. S. Yadav. Synthesis, 2010, 505-509. 
7. International Application published Under The Patent Cooperation Treaty (PCT). Process For The Preparation Of ASENAPINE Intermediate. Inventors: SHARMA, Ramnic; H. No. 1012, 2nd Floor, Sector 17B, Gurgaon, Haryana 122015 (IN). ALLU, Senkara, Rao; s/o Bheemu Naidu, Narasimha Puram, Gedda Kancharam, Metta Palli, Srikakulam, Andhra Pradesh 535125 (IN). ARYAN, Ram, Chander; 1066, Sector-A, Pocket-A, Vasant Kunj, New Delhi 110070 (IN). International Publication Number: WO 2013/080069 A1

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